What is S-ketamine?

• 🧬 The S-(+) isomer of ketamine.
• 💊 Available as a prescription medication in some countries for treatment-resistant depression (administered under medical supervision).
• 🏥 Also used in some medical settings for anesthesia and pain management.

Potential Benefits

🧠 Mind

• 🌤️ Rapid antidepressant effects for some people with treatment-resistant depression.
• 💙 May reduce symptoms of depression within hours to days.
• 🧘 Can improve mood and emotional resilience.
• 💭 May help interrupt persistent negative thought patterns.
• 🤝 Can enhance the benefits of psychotherapy when appropriately integrated into treatment.

💪 Body

• 🩹 Effective anesthetic at appropriate medical doses.
• ⚡ Can provide pain relief, especially for certain acute or chronic pain conditions.
• 😌 May promote relaxation during supervised treatment.

Common Side Effects

• 😵 Dizziness
• 😶 Dissociation (feeling detached from yourself or your surroundings)
• 🤢 Nausea
• 😴 Drowsiness
• 👁️ Blurred vision
• ❤️ Temporary increases in blood pressure and heart rate
• 🤕 Headache

S-ketamine vs. R-ketamine

• S-ketamine (esketamine): More potent at certain receptors and currently approved in some regions for specific medical uses such as treatment-resistant depression.
• R-ketamine: Still being studied. Early research suggests it may have antidepressant effects with potentially fewer dissociative side effects, but it is not widely approved as a medication.